What is CMV?

CMV is a common virus that many adults and children contract in their lifetime. Though mostly asymptomatic, it can be passed from a pregnant mother to her unborn child.

CMV is the leading infectious cause of birth defects in the United States with approximately 25,000 newborns in the U.S> infected every year.1,2

Approximately 20% of infected infants will have birth defects that include neurodevelopmental disabilities such as hearing loss, vision impairment, varying degrees of learning disability and decreased muscle strength and coordination. 3

Currently, there is no approved vaccine for the prevention of CMV infection.

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CMV Parent, Farah sits down with Moderna's Drew Nathenshon to honor and remember her daughter Maddie who passed away due to complications associated with CMV 12 days after her birth.

CMV Parent, Cara sits down with Moderna’s Patrick Bergstedt to talk about the first time she heard of CMV. Cara speaks about an informed parenting approach with her 7 year old son, Parker and how she continues to do it all to make sure he leads a life of success.

CMV parents, Ashley and Nic sit down with Dr. Lori Panther to discuss their daughter iya’s CMV diagnosis, and how it sparked their activism around CMV education for families and pregnant moms-to-be.

We are celebrating National CMV Awareness Month with CMV voices: Hear from Acantha on her experience as a CMV mom

Moderna colleagues raise their hands to “stop CMV” as part of National CMV Awareness Month in June. 

Developing a CMV Vaccine

June is National CMV Awareness Month! Moderna will be sharing stories to amplify CMV voices all month

Moderna's mRNA Approach to a CMV Vaccine

Moderna's messenger RNA (mRNA) platform directs cells to safely produce and express antigenic proteins that trigger the body's immune system to produce antibodies that can neutralize the virus and prevent infection.

Moderna's mRNA vaccine combines six mRNAs (five encoding for the pentamer complex and one encoding for gB) together into one vial.

A vaccine that stimulates strong antibody response against these antigens is expected to prevent CMV infection, and women protected from CMV infection by a vaccine would be protected from having a child with congenital CMV infection.

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Learn more about CMV

and how you can get involved, visit:

National CMV Foundation                 CDC               March of Dimes

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1 Congenital CMV and Hearing Loss. Centers for Disease Control and Prevention. Available at https://www.cdc.gov/cmv/hearing-loss.html.  
2  Schleiss et al. Progress toward development of a vaccine against congenital cytomegalovirus infection. Clinical and Vaccine Immunology. 2017; 24(12): e00268-17. 
3  Congenital CMV and Birth Defects. American Pregnancy Association. Available at: https://americanpregnancy.org/birth-defects/congenital-cmv-birth-defects/