Advancing mRNA Medicines to Fight and Prevent Disease

At Moderna, we are driven by our mission to deliver on the promise of mRNA science to create a new generation of transformative medicines for patients. We are currently advancing mRNA development candidates to address serious unmet needs across several therapeutic areas and multiple diseases. Clinical (human) trials are now underway for several of our investigational mRNA vaccines and therapeutics.

Below is a list of clinical trials for which Moderna is actively recruiting participants. We have provided links to the study listings on, where you can find more information, including details on eligibility criteria and clinical trial locations.

If you are seeking additional information, please email

Actively Recruiting Clinical Studies

Infectious Disease Studies

Disease Program Study Phase Study Focus More Info

Cytomegalovirus (CMV)

Prophylactic Vaccine

Phase 1

Safety, reactogenicity, and immunogenicity of Cytomegalovirus Vaccines mRNA-1647 in Healthy Adults


Cancer Studies

Disease Program Study Phase Study Focus More Info
Solid tumors  

Personalized Cancer Vaccine

Phase 1 Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone in Subjects with Resected Solid Tumors and in Combination With Pembrolizumab in Subjects With Unresectable Solid Tumors (KEYNOTE-603)
Advanced / metastatic
solid tumors
or lymphoma

Intratumoral Immuno-Oncology

Phase 1

Dose Escalation Study of mRNA 2416 for Intratumoral Injection to Patients with Advanced Malignancies