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22 October 2025

IR Insights: An Update on Moderna’s CMV Program

Moderna
IR Insights: An Update on Moderna’s CMV Program

Earlier today, Moderna announced the Phase 3 results for its investigational cytomegalovirus vaccine.

Stéphane Bancel, CEO, and Stephen Hoge, President, sat down for an episode of IR Insights to give additional context. Watch the episode here:  

Forward-Looking Statements 

This post and accompanying video contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including statements regarding: Moderna’s 2025 financial guidance and its expectation of achieving breakeven in 2028; the potential of mRNA-1647 for bone marrow transplant patients and Moderna’s ongoing Phase 2 trial; the potential of Moderna’s prioritized portfolio; anticipated milestones for Moderna’s pipeline programs, including potential regulatory submissions in 2025; Moderna’s belief that there is minimal read-through from the mRNA-1647 trial to the broader platform; and the potential of Moderna’s oncology portfolio. In some cases, forward-looking statements can be identified by terminology such as “will,” “may,” “should,” “could,” “expects,” “intends,” “plans,” “aims,” “anticipates,” “believes,” “estimates,” “predicts,” “potential,” “continue,” or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. The forward-looking statements in this post and accompanying video are neither promises nor guarantees, and you should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond Moderna’s control and which could cause actual results to differ materially from those expressed or implied by these forward-looking statements. These risks, uncertainties, and other factors include, among others, those risks and uncertainties described under the heading “Risk Factors” in Moderna’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024, filed with the U.S. Securities and Exchange Commission (SEC), and in subsequent filings made by Moderna with the SEC, which are available on the SEC’s website at www.sec.gov. Except as required by law, Moderna disclaims any intention or responsibility for updating or revising any forward-looking statements contained in this presentation in the event of new information, future developments or otherwise. These forward-looking statements are based on Moderna’s current expectations and speak only as of the date of this post. 
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