A New Approach to Medicine

Using mRNA as a drug, because it causes the expression of proteins inside cells, is a fundamentally different approach than treating disease with other drug classes.

mRNA plays a very fundamental role in human biology. mRNA is the set of instructions by which cells make all proteins and send them to various parts of the body.

By using mRNA as a drug, we take advantage of normal biological processes to express proteins and create a desired therapeutic effect. This enables the potential treatment of a broad spectrum of diseases, many of which cannot be addressed with current technologies. mRNA also enables our scientists to design, discover and develop therapeutics that replicate many aspects of normal biology.

With these features, mRNA has the potential to transform how medicines are discovered, developed and manufactured – at a breadth, speed and scale not common in our industry.

The Science of mRNA

We are leveraging the central role that mRNA plays in human biology. Our mRNA medicines are sets of instructions that cells in the body use to make proteins to prevent or fight disease.
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Our mRNA Platform

mRNA is like software for the cell. And if it works for one disease, it should work for many diseases. Our approach to leveraging mRNA science started with creating an operating system – our multidisciplinary mRNA platform technology. 
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Research Engine

Our research engine enables scientists across our ecosystem to get large quantities of high-quality research mRNA in an expedited timeframe in order to undertake rational design of mRNA medicines.
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Early Development Engine

Our early development engine enables us to move many development candidates simultaneously into and through GLP toxicology, Phase 1 and Phase 2 studies to human proof of concept. 
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Technology Strategy

To apply the disruptive technology of mRNA to the biopharma world, we’re developing modalities that are solution sets enabling the creation of multiple technologically similar drugs with applications across therapeutic areas and diseases. 
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